Polymorphism of fecundity genes (BMP15 and GDF9) and their association with litter size in Bangladeshi prolific Black Bengal goat

Goat farming in Bangladesh is primarily centred on indigenous Black Bengal goat, a highly prolific breed. Searching for genetic markers associated with prolificacy this breed vital the country’s goat breeding industry. However, there are no reports polymorphisms fertility of Bangladeshi goats. This study investigated two major fecundity genes-bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) to detect any possible mutations these genes litter size Blood samples were collected from 40 raised goats Hathazari Government Farm, Bangladesh. Genomic DNA was extracted; PCR amplification performed; sequencing products performed polymorphism loci target genes. Five SNPs viz. C735A, C743A, G754T, C781A C808G detected exon 2 BMP15 gene. A SNP (T1173A) GDF9 2. Association results show that at 735, 754 781 nucleotide positions had significant association goat. The effect parity also (P < 0.001) size. For first time, explored Further studies many genetically unrelated animals assessing others may be useful.